The honest man takes pains, and then enjoys pleasures; the knave takes pleasures, and then suffers pains.
Franklin contrasts two sequences of behaviour. The honest person accepts effort, restraint or difficulty first and enjoys the benefits afterwards. The dishonest person seeks immediate pleasure or advantage, but later faces the consequences. The saying therefore links ethical conduct with a willingness to bear short-term costs rather than avoiding them through deception or irresponsibility.
The contrast is deliberately simplified and should not be read as a guarantee that honest people will always prosper or that wrongdoers will always suffer. Franklin’s broader point concerns the order of effort and consequence. Responsible conduct may involve inconvenience at the outset, but it can produce greater security and peace of mind later. By contrast, immediate gratification gained through misconduct may simply postpone the cost, leaving regret, punishment or other difficulties to be dealt with afterwards.