To speak well of a base man is much the same as speaking ill of a good man.
Leonardo’s remark argues that praise can distort moral judgement just as criticism can. Speaking favourably of someone whose conduct is seriously objectionable may give that person undeserved credibility, in much the same way that speaking unfairly against a good person can damage a deserved reputation.
The statement therefore treats praise and blame as forms of judgement that carry consequences. Approval is not presented as neutral: it can influence how others understand a person’s character and actions. Leonardo’s comparison suggests that misplaced praise may weaken standards of judgement by making harmful or dishonourable conduct appear worthy of respect.
The quote can be applied when considering endorsements, recommendations and public assessments of character. Its broader point is that praise should be proportionate to conduct and evidence, just as criticism should be. Both can mislead when they are detached from a fair assessment of how a person has acted.